Happy Halloween with Osirix: A Pumpkin MRI

It's that time of year...and what better way to celebrate Halloween than with a MRI of a pumpkin, rendered via Osirix imaging software? Can you see the seeds inside?

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© Fran Jurga and Hoofcare Publishing; Fran Jurga's Hoof Blog is a between-issues news service for subscribers to Hoofcare and Lameness Journal. Please, no use without permission. You only need to ask. This blog may be read online at the blog page, checked via RSS feed, or received via a digest-type email (requires signup in box at top right of blog page). To subscribe to Hoofcare and Lameness (the journal), please visit the main site, www.hoofcare.com, where many educational products and media related to equine lameness and hoof science can be found. Questions or problems with this blog? Send email to blog@hoofcare.com.  

Follow Hoofcare + Lameness on Twitter: @HoofcareJournal

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Disclosure of Material Connection: I have not received any direct compensation for writing this post. I have no material connection to the brands, products, or services that I have mentioned, other than Hoofcare Publishing. I am disclosing this in accordance with the Federal Trade Commission’s 16 CFR, Part 255: Guides Concerning the Use of Endorsements and Testimonials in Advertising.

Silent Anvil: Kevin Howes' Video Would Have Brightened a Rainy Day

I believe it was 2009 when British farrier Kevin Howes of Ridgeway Forge Farriers starred in this video about what it's like to be a farrier for Kent Television and the general promotion of British farriery.

I've always meant to post it on the blog, but now regret that I saved this one for a rainy day.

Kevin was killed in a car accident a few days ago in the county of Kent, England where he lived and served as farrier at the Kent County Show.

It's terribly sad to learn of anyone's death. A very moving article on the website Kent Online about Kevin Howe's death mentions that he underwent skin cancer surgery for a malignant tumor while in apprenticeship, and that he completed college and his apprenticeship even though he struggled with dyslexia.

Another article about Kevin and his work can be read on the This Is Kent news site.

Among the racehorses credited to Kevin Howes was the 2006 Cheltenham Gold Cup winner, War of Attrition.

David Chapman Jones, founder of Tendonology, worked with Kevin Howes and remembers: “Kevin was a first class farrier who I trusted totally with the racehorses in my care for tendon treatment. Many top class racehorses are racing today thanks to Kevin's expertise. He was a pleasure to work with and what set him apart was his creativity, imagination and desire to solve a problem. There are so many cases we dealt with where I can say that Kevin's knowledge was as much a part of the treatment process as my input."

Moral of the story: Don't be leaving too many things for a rainy day. It's about time Kevin's upbeat tribute to the job he obviously loved had its day on The Hoof Blog, but I never thought it would be with this news attached to it.

 TO LEARN MORE

© Fran Jurga and Hoofcare Publishing; Fran Jurga's Hoof Blog is a between-issues news service for subscribers to Hoofcare and Lameness Journal. Please, no use without permission. You only need to ask. This blog may be read online at the blog page, checked via RSS feed, or received via a digest-type email (requires signup in box at top right of blog page). To subscribe to Hoofcare and Lameness (the journal), please visit the main site, www.hoofcare.com, where many educational products and media related to equine lameness and hoof science can be found. Questions or problems with this blog? Send email to blog@hoofcare.com.  

Follow Hoofcare + Lameness on Twitter: @HoofcareJournal

Read this blog's headlines when you "like" the Hoofcare + Lameness Facebook Page

 

Disclosure of Material Connection: I have not received any direct compensation for writing this post. I have no material connection to the brands, products, or services that I have mentioned, other than Hoofcare Publishing. I am disclosing this in accordance with the Federal Trade Commission’s 16 CFR, Part 255: Guides Concerning the Use of Endorsements and Testimonials in Advertising.

A Slice of Life: Behind-the-Scenes of Equine Anatomy with Dr. Christoph von Horst

Suppose you could suspend the animation of a bird or a fish or a horse...by preserving its anatomy in whatever angle or gesture or exposure you wished. That's the power that Germany's Christoph von Horst wields in his plastination laboratory.

Everything that was once alive not only lives again, but lives forever. It may no longer be living and breathing, but it's catching light and revealing its form to anyone who cares to have a look. And it has taken on an artistic, minimalist power.

You've heard plastinate slices of hoof tissue called "living X-rays" before; now we have living MRIs! (image © Christoph von Horst and Hoofcare Publishing)

Dr. von Horst's company, HC Biovision, is the world's leader in preserving anatomical specimen for educational and exhibition purposes. We are fortunate that he finds the horse's foot especially fascinating. He has been encasing microscopically thin slices of hoof tissue in Lucite for several years now, and has created a portfolio of hoof pathology to rival any in a museum.

A horizontal section of plastinated hoof tissue reveals a slice-by-slice tour of a horse's hoof anatomy (image © Christoph von Horst and Hoofcare Publishing)

Dr. von Horst will visit the USA this month; he will be helping Hoofcare Publishing introduce a new collection of plastinated hoof tissue specimen at the International Equine Conference on Laminitis and Diseases of the Foot in West Palm Beach, Florida this weekend, October 29-31.

He visited previously this year to speak at the international plastination conference at the University of Toledo and the annual convention of university veterinary anatomists at Cornell University.

Keep a hoof in your pocket; this new technique, called the "basic hoof" is impregnated with plastic but not cased in Lucite. Basic hooves cost only $50US (plus shipping) and will fit in your pocket. No two are alike!

Each plastinate is treated to resist light damage and will not fade. The cost on most blocks is $200. Most are about an inch thick and will stand up on their own.  But relief "basic" hooves start at $50--without plastic casing, just plastic impregnating the hoof tissue--and the "sheet", or thin plastic casings are $95 each.

Plastinates have many applications in the way that professionals interact with each other and with clients. On another level, they are used in anatomy education and on still another, for corporate use in detailing product or service details. When a veterinarian needs to explain why a horse with a fetlock problem might benefit from a course of Legend, this "slice" is an inexpensive, indestructible, reusable and portable tool for showing a typical fetlock to a client. (Christoph von Horst image)

Please contact Hoofcare and Lameness if you are looking for a unique gift, award, trophy, or a real treat for your own study of the hoof. Navicular damage and chronic laminitis samples are available as real models or in laminated poster form for reference, with areas of interest like the toe of a laminitic foot or a cross-section of a navicular bone and its ligaments greatly enlarged.  Sheet plastinates of the distal limbs of foals clearly show the growth plates and are perfect for explaining to horse owners why their horses need therapy sooner instead of later.

Dr Denoix's book is the perfect companion to plastinated specimen. Highly recommended for reference for academic or professional use of specimen or diagnostic images. It is simply "THE" book to have on hand. Call 978 281 3222 or email Hoofcare + Lameness to order your copy. A superb gift!

Ohio State Belknap Grant: Laser Capture Microdissection in Equine Laminitis

via press release

The Center for Clinical and Translational Science (CCTS) Pilot and Collaborative Translational and Clinical Science Program at The Ohio State University has awarded James Belknap, DVM, PhD, a pilot grant to be used for his research of equine laminitis.

Laminitis is a crippling disease that affects horses. Similar to organ injury in humans with sepsis, it entails an inflammatory injury of the laminae, a soft tissue (of the same cell types that make up our skin) which interdigitates to support the horses’ third phalanx (coffin bone).

This life threatening disease is extremely painful and can be onset by colic, enterocolitis, pleuropneumonia, and metritis.

“It is a devastating disease,” Belknap said. As an equine surgeon, he commonly treats clinical cases of the disease at the OSU Veterinary Teaching Hospital.

Belknap believes that the first step to fighting laminitis is to find out what signaling events in the foot prompt the disease to occur.

“There is a layer of cells attached to the hoof wall called the basal epithelial cells that lose their attachment to the underlying connective attached to the third phalanx,” Belknap said. This detachment results in the third phalanx tearing loose from the hoof wall and displacing toward the ground.

“It can actually perforate the sole. We need to find out what signaling is going on in these cells that causes them to lose their adherence,” Belknap said.

In order to find out what the signaling events are, the team is using laser capture microdissection to collect and isolate RNA samples from laminar epithelial cells.

“At this point it’s sort of a black box of what’s going on with these cells,” said Belknap.

By using laser capture microdissection to collect the specific layer of cells at the point of failure, a better understanding of the role that the laminar epithelial cells play in this disease will become clear.

Graduate student Britta Leise, MS, DVM, is working in the Belknap laboratory to collect the RNA samples. Once the cells have been collected by Leise, they will be sent to Texas for microarray analysis and gene networking. The cells afflicted with laminitis will be compared to those of clinically normal horses.

“The analysis of these data will focus in on the cellular dysregulation that result in structural failure of the digit in the disease,” Belknap said.

Once the points of dysregulation are identified, Belknap believes that it would be more likely to find an effective combination of medical treatments to combat the crippling disease.

Dressage, Fuego-Style: It's What's Underneath That Counts as Euro Rocker Shoes Score for Spain

Update: The horseshoe explained in this article is the subject of an update post published 18 February 2012 with a dressage horse in California. Be sure to click on this link after you read this original story: ON THE (Dressage) CASE: Euro Rock ‘n Roll Horseshoe Evolves with Vet-Farrier Collaboration, California Style

Fuego XII, now known as Fuego de Cardenas, is one of the top ten FEI dressage horses in the world, and probably the most successful FEI dressage horse in Spanish history. Spanish horses are usually short-backed and great at piaffe but lack the extension of the northern European warmbloods. But the Spaniards are working on that...(Mrs. Flax photo)

When the great Spanish dressage horse enters the arena at an FEI musical freestyle event, you know who it is. You hear that staccato Spanish flamenco music and he starts piaffing in perfect time.

But underneath, that horse is pure rock n roll.

Although someone suggested that, when it came time for The Hoof Blog to show his shoes, the soundtrack should change to the theme from Twilight Zone.

In the past, we’ve shared the news that the USA’s top dressage horse, Ravel, ridden by California’s Steffen Peters, won the FEI World Cup in high-tech plastic Epona shoes. And that when triple-world champion Totilas left The Netherlands, his new German management team switched his minimalist steel Rob Renirie open-heeled shoes for heart bars.

Laminitis in a Moose? Vermont's "Pete the Moose" Isn't the First--Just the Most Famous--Moose to Founder

The state of Vermont is astir today with the news that one of its most beloved--and controversial--residents has succumbed to what is being called "laminitis". The latest victim of the merciless foot disease is not one of the Green Mountain State's signature Morgans. It's not an iconic draft horse on one of the dairy farms. It's not even a backyard pony.

This time laminitis--or something like it--has led to a sad ending for a moose.

Not just any moose, mind you, but Pete the Moose. And the citizens want to know what's been going on.

First, the setting: Vermont's Northeast Kingdom. A section of the United States inhabited by far fewer people than animals, and visited by even fewer. That said, it is one of the most beautiful places on earth. You just can't quite get there from here. Or anywhere. It's a corner of Vermont wedged between Quebec and New Hampshire, but that doesn't really matter because you probably won't ever have a reason to go there.

These might be considered "normal" moose claws, or hooves. (Cathleen Shattuck photo)

Then, some background: Pete was injured as a mooseling. He was attacked by dogs and left to die. But he was nursed back to health for over a year by David the Vermonter. They became attached, best buddies, an odd couple in the interspecies world order of things. Things got messy when the state government ruled that David didn't "own" Pete. They decided that if Pete couldn't live on his own in the wild, it would be all right if Pete went to live in a hunting preserve with some imported elk.

Then the state had second thoughts. Things got even messier. Just suppose one of those elk had a disease like BSE, or "chronic wasting disease" (think: a wildlife version of mad cow disease) and Pete contracted it. Then suppose somehow Pete escaped and went back into the wild and spread the disease around Vermont.

Enter: lawyers, courts, the governor. Was this a wildlife issue or an agriculture crisis? Pete received the death sentence. But wait! Then the governor (also named Pete) stepped in and pardoned him, forcing a stay of execution.

An ABC-TV news segment on Pete in late 2009

Pete became quite a celebrity. He had over 6000 "friends" on Facebook. If you can have a big cat or a poisonous snake for a pet, why can't David have a moose?

A video of David, Pete's friend, when the state government was threatening to "remove" Pete. He was living in a 600-acre private game sanctuary for elk at the time but the state thought he was a public health risk. 

Things went quiet for a while. We didn't hear anything about Pete. Then he turned up dead. Or didn't turn up, as the case may be.

The news this morning from Vermont is that Pete died on Labor Day when "tranquilized" (no further information given) in order to have his hooves trimmed.

Vermont Fish &Wildlife Department Commissioner Patrick Berry said in a press statement: "Most of the people who have been fans of Pete the Moose have never fully understood the story," he said. "It's not a good idea to trap wildlife behind a fence and feed them beer and doughnuts. This is a good example of what happens when you don't keep wildlife wild."

"The hoof condition he was being treated for likely was caused by eating corn and other foods not part of a moose’s normal diet during his years in captivity," Berry is quoted as saying in the Burlington Free Press.

According to ABC News, Pete enjoyed munching on apples, bananas and Snickers candy bars but refused to eat Milky Ways.

Meanwhile, Pete's body disappeared. According to state law, the carcass needs to be tested for chronic wasting disease.

So in the Northeast Kingdom of Vermont, there may still a moose on the loose  but someone is going to need to produce a carcass.

Laminitis in moose around the country may actually be on the rise. North Dakota is one state that is concerned about the problem, as moose migrate into farmland and feed on grain. A study by Butler et al followed a series of necropsies on four moose believed to have died from grain overload. In particular, "Case A" from that study was described: "... was in good body condition and was presented at necropsy with moderate postmortem change. It was noted that all 4 digits had severely overgrown claws. The hind and front claws were approximately 30 cm and 20 cm longer than normal, respectively. Separation of the dorsal claw from the third phalanx was evident. Severe congestion was noted around the distal aspects of the third phalanx in both front digits.... A diagnosis of severe, chronic laminitis in all 4 feet was made." That paper was published in Alces, the journal of moose.

A paper published by the University of Zurich chronicled a zoo moose diagnosed with laminitis. Postmortal radiographic diagnosis of laminitis in a captive European moose (Alces alces) by Clauss et al is available as a free pdf download.

"Abnormal keratinazation" on the Redoubt Blog

In 2009, the Redoubt Reporter on the Kenai Peninsula in Alaska marveled when a moose was hit on the highway and its hooves proved to be at least 6-10 inches longer than normal. (See photo.)

Research going back to 1977 in Alaska begs the definition of what laminitis is. Indications of Copper Deficiency in a Subpopulation of Alaskan Moose by Flynn et al described a copper and sulfur deficiency that caused abnormal keratinization of moose hooves. "Faulty keratinization was linked with copper deficiency by both mineral element analyses and photoelectron spectroscopy. Decreased copper and sulfur hoof content and an abnormal electron spectroscopy chemical analysis (ESCA) spectra indicated incomplete sulfur cross-linking in the hoof keratin."
According to the European Bioinformatics Institute, keratinization is defined as "the process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns."

That paper was published in the Journal of Nutrition and can be downloaded for free by clicking on the link.

Hoof deformities of elk have also been studied; a poster presentation showing anatomical specimen can be viewed as a free-download pdf file: Severe Hoof Deformities in Free-Ranging Elk in Western Washington State by Han et al.

Who knows what killed Pete the Moose? Someone somewhere does, and maybe the truth will out. The latest news reports are stressing that an error or adverse reaction in the use of the tranquilzer probably actually killed Pete, but still more information is needed about what was wrong with his hooves.

There is no doubt, however, that some sort of hoof condition is becoming common in moose across North America. Shall we blame it on global warming? Acid rain? Encroaching civilization?

One thing is for sure: it's not the moose's fault, and the relatively recent onset of the problem suggests that maybe something can be done to help these most fascinating animals stay on their feet. Something's not right but in studying abnormal moose hooves perhaps we'll learn something about horses, too.

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Moosewatch blog from Utah: A kind human has been feeding a wild moose horse feed and hay. Includes photos of the moose's deformed claws. Interesting to see that the deformity is visible on both lateral claws of the front feet.

Presentation "Moose Management in North Dakota" by William Jensen, North Dakota Department of Fish and Game at the Minnesota Moose Summit, 2008.

© Fran Jurga and Hoofcare Publishing; Fran Jurga's Hoof Blog is a between-issues news service for subscribers to Hoofcare and Lameness Journal. Please, no use without permission. You only need to ask. This blog may be read online at the blog page, checked via RSS feed, or received via a digest-type email (requires signup in box at top right of blog page). To subscribe to Hoofcare and Lameness (the journal), please visit the main site, www.hoofcare.com, where many educational products and media related to equine lameness and hoof science can be found. Questions or problems with this blog? Send email to blog@hoofcare.com.  

Follow Hoofcare + Lameness on Twitter: @HoofcareJournal

Read this blog's headlines in your Facebook news feed when you "like" the Hoofcare + Lameness Facebook Page

 

Disclosure of Material Connection: I have not received any direct compensation for writing this post. I have no material connection to the brands, products, or services that I have mentioned, other than Hoofcare Publishing. I am disclosing this in accordance with the Federal Trade Commission’s 16 CFR, Part 255: Guides Concerning the Use of Endorsements and Testimonials in Advertising.