Showing posts with label disease. Show all posts
Showing posts with label disease. Show all posts

Friday, May 18, 2012

Acute Laminitis Medication Available to Field Case(s) for Testing


SPONSORED HOOF BLOG POST

Laminitis #2

WANTED: YOUR NEXT ACUTE LAMINITIS CASE

MAY 18, 2012--Hoofcare Publishing is asking the blog readership for assistance. The developer of a promising medication to improve the prognosis of acute laminitis cases is seeking a collaborator in the field who has a case that has just been diagnosed.

The medication is a mast cell inhibitor (stabilizer) that has been FDA-approved for use in humans. It is designed to inhibit the release of inflammatory mediators from the cells involved in laminitic reactions and has been successfully tested as a medication for induced laminitis in cattle, sheep and horses in university and private test studies.

B0004150 Mast cell showing histamine granules
A mast cell contains a bundle of granules. When it is activated, the pink granules, in this case of histamine, are released.  Mast cells are important in the immune response system but have many functions that are being studied in medicine. Color-enhanced transmission electron microscope image credit: University of Edinburgh. Wellcome Images
The developer now needs some clinical tests of the drug, which ships in solution in a vial. It is injected into the foot via retrograde venous therapy, similar to the way that antibiotics are injected into feet with infections. A tourniquet is used at the fetlock and the medication, in solution, is injected into the digital vein.

Only acute laminitis cases are being sought at this time. Horses that have progressed to chronic laminitis are not suitable for this test.

B0002677 Mast cell releasing histamine granules
A stimulated mast cell that has just exploded, releasing histamine granules. The remains of the cell are seen towards the lower left, still containing a number of granules that are yet to escape. Image credit: K. Whitley, D. Becker, Wellcome Images
The medication is a mast-cell stabilizer, meaning that it inhibits the release of excess inflammatory mediators contained within mast cells. This is a much-studied area of immune-response medicine and other areas of disease pathways. The laminitis formulation also offers anti-inflammatory properties but must be administered only to horses that are not receiving Bute for therapy.

 A $75 formulation fee will be waived to a Hoofcare + Lameness blog reader who comes forward with a case to participate.

A clinic or private practitioner who would like to participate agrees to:

a. Administer the drug via the retrograde administration instructions provided.

b. Complete a Post-Treatment – Results Form – “5-Days” Post-Treatment.

c. To allow study sponsor to contact horse owner to complete Post-Treatment survey.

d. An owner-consent form must be completed.

If you are interested in participating, please send an email to Hoofcare Publishing and the developer will contact you.

Caution: Federal (United States) Law restricts this drug to use by or on the order of a licensed veterinarian.   Storage requirements: Room Temperature 

Followup: this product is also known as Laminil 
 
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Tuesday, April 03, 2012

Grass Laminitis: What You Don’t Know Can Hurt You (and Your Horse) and Surprise the Researchers

New ad promo and publicity from Boehringer-Ingelheim Vetmedica perhaps oversimplifies grass laminitis. But it might get the attention of horse owners.
When it comes to laminitis, I feel like a whirling dervish: what’s going on in Australia, what’s going on in Europe? what’s going on here in the USA? (whirl)

Saturday, March 03, 2012

Equine Laminitis: 2012 Video Education Update from the Animal Health Foundation

The Animal Health Foundation, a non-profit organization that funds laminitis research at Dr Chris Pollitt's Australian Equine Laminitis Research Unit and at universities in the United States, has assembled a quick course update for horse owners and horse professionals on preventing, managing and treating the disease of equine laminitis.

While there is still much that we don't know about laminitis, Donald Walsh, DVM has prepared a primer that should make clear the current state of practical information.

Please watch all five videos in the Animal Health Foundation's EQUINE LAMINITIS 2012 UPDATE and share these videos with everyone in the horse world. This is important information.



1 INTRODUCTION TO LAMINITIS
Does your horse have laminitis or founder? Would you like to prevent the disease? Are you concerned about the dangers of insulin resistance, obesity, over-grazing and hoof condition changes? Have you been told your horse is at risk for laminitis? If you answered yes to any of those questions, this educational video series could save your horse's life. Five concise, free, non-commercial videos from the non-profit Animal Health Foundation offer the latest practical and scientific information to help you help your horse avoid or overcome laminitis in its many forms. Your host: Donald Walsh, DVM, founder of the Foundation and a practicing veterinarian who specializes in laminitis and founder.


2 UNDERSTANDING EQUINE LAMINITIS: HOW DOES LAMINITIS OR FOUNDER AFFECT YOUR HORSE?
What happens in horses' feet during laminitis? What's the difference between laminitis and founder? You will learn three different ways that a horse gets laminitis and the many causes, including Equine Metabolic Syndrome and Cushing's Disease, or "PPID", and support-limb laminitis. The non-profit Animal Health Foundation and Dr. Donald Walsh offer the latest practical and scientific information to help you and your horse avoid or overcome laminitis in its many forms.


3 WHAT CAN YOU DO IF YOUR HORSE HAS "ACUTE" LAMINITIS?
Can you recognize "acute" (sudden onset) laminitis symptoms? How can you help your horse during this medical emergency? Dr. Walsh encourages horse owners to employ the only scientifically-proven method to prevent laminitis: "icing the feet" , or "cryotherapy". Does your horse need blood insulin tests to find the cause of the laminitis? The non-profit Animal Health Foundation and Dr. Donald Walsh offer the latest practical and scientific information to help you help your horse avoid or overcome acute laminitis.


4 CHRONIC LAMINITIS AND FOUNDER
Chronic laminitis means a life of ongoing, crippling pain for horses. What can a horse owner do? Dr. Walsh explains long-term ("chronic") laminitis and current methods of hoof mechanics to support damaged feet. He explains abnormal hormones and that Cushing's disease ("PPID") or Equine Metabolic Syndrome may be the underlying cause. You'll learn about hay testing and benefits of soaking hay in water. Finally, Dr. Walsh speaks frankly about putting some horses to sleep because of advanced laminitis.


5 PREVENT LAMINITIS IN YOUR HORSE
What are the best horsecare practices to protect your horse from laminitis? What are the risk factors? Can icing the feet help? What might a cresty neck or hoof rings mean? You'll learn to recognize early changes in your horse's feet before laminitis occurs and how to correct hormone levels before horses go lame. Dr Walsh suggests ways to prevent supporting limb laminitis in horses with leg injuries.


LAMINITIS RESEARCH. This video, made in 2011, explains the priorities of laminitis research in Dr. Pollitt's Australian Equine Laminitis Research Unit, which is funded in many of its projects by the Animal Health Foundation. It contains the core principles of the AHF concern to make laminitis research relevant and helpful to real people and real horses. Other studies funded by AHF have included genetic studies at Cornell University, endocrine studies at the University of Missouri and Cornell, and Katy Watts' innovative "Safer Grass" studies to analyze how grass founder might be prevented.

The Animal Health Foundation depends on large and small donations to fund research projects. All donated funds go directly to research; the foundation is run by volunteers including Dr. Walsh, whom you met in the video.

Further Animal Health Foundation research will enable us to prevent laminitis and "Free the Horse of this Disease".

Learn more about the Foundation and how you can donate or become involved in the fundraising process.

Thank you.

© Fran Jurga and Hoofcare Publishing; Fran Jurga's Hoof Blog is a between-issues news service for subscribers to Hoofcare and Lameness Journal. Please, no use without permission. You only need to ask. This blog may be read online at the blog page, checked via RSS feed, or received via a digest-type email (requires signup in box at top right of blog page). To subscribe to Hoofcare and Lameness (the journal), please visit the main site, www.hoofcare.com, where many educational products and media related to equine lameness and hoof science can be found. Questions or problems with this blog? Send email to blog@hoofcare.com.  
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Disclosure of Material Connection: I have not received any direct compensation for writing this post. I have no material connection to the brands, products, or services that I have mentioned, other than that I serve on the Board of Directors of the Animal Health Foundation, which is a volunteer position. I am disclosing this in accordance with the Federal Trade Commission’s 16 CFR, Part 255: Guides Concerning the Use of Endorsements and Testimonials in Advertising.

Thursday, November 03, 2011

Prascend® PPID (Equine Cushings Disease) Treatment Approved by FDA for US Horses


Maybe I'm biased, but I thought that the CSI (Cushings Scene Investigation) ad run by Boehringer-Ingelheim Vetmedica in British horse magazines was the most clever horse ad so far this year. It heralded the introduction of Prascend to treat Cushings-suffering horses; Prascend will soon be available in the USA.

The following press release is not an ad, it is published here as a "heads up". Anyone involved in the world of Hoofcare + Lameness is going to hear about this. Farriers and veterinarians will be asked questions by horseowners about this medication, and you need to know about how pergolide has evolved into Prascend®.

Prascend has been available in the United Kingdom for a few months, and Boehringer-Ingelheim Vetmedica has launched an awareness campaign there to urge horse owners to have their horses tested for PPID. I don't know yet what B-I has planned in the USA, but I feel confident in saying that "this is news".

In 2007, this blog reported that a potential crisis loomed for horseowners who were treating the symptoms of their horses' PPID condition with Permax (pergolide). (See links at end of this blog post.) The medication was taken from the market temporarily because of problems with human prescriptions. Before long, it became available again in the compounded form, which many horse owners ordered directly and in different forms.

Compounding pharmacies have been at the center of a controversy in the veterinary industry. At this time, it is too early to give a reliable answer whether compounded (and less expensive) pergolide will remain an option for horseowners as pill-only Prascend enters the marketplace. Ideally, horseowners will have safe and multiple alternatives to keep their horses comfortable.

Much more information will be available at or following the AAEP Convention in San Antonio later this month.
 

Everyone can recognize the advanced PPID (Cushing disease) horse. But laminitis and stretched white lines in younger horses may not seem to be related to PPID until much later, when a definitive diagnosis is made. Only careful testing will discern if horses without obvious signs suffer from PPID. (photo provided by Dr. Christian A. Bingold)

Boehringer Ingelheim’s Prascend® Approved for PPID in Horses
Product is the first and only FDA-approved treatment for the management of PPID.

ST. JOSEPH, Mo. (November 2, 2011) – Boehringer Ingelheim Vetmedica, Inc. (BIVI), has received approval from the Food and Drug Administration (FDA) to market Prascend® (pergolide mesylate), for treatment of clinical signs associated with pituitary pars intermedia dysfunction (PPID), also known as equine Cushing’s disease.

PRASCEND is the first and only FDA-approved product for the management of PPID in horses. (1) Administered in tablet form, treatment with PRASCEND can improve the quality of life for PPID-affected horses by managing clinical signs and decreasing the risk of complications of the disease, including those that have the potential to be life-threatening.

It is estimated that one in seven horses over the age of 15 has PPID (2) and horses as young as seven years of age have been diagnosed with the disease (3). In addition, up to 70 percent of clinical laminitis cases also may be affected with underlying PPID4. The most common clinical signs of advanced-stage PPID that occur in horses are hirsutism (hypertrichosis) or an abnormal amount of hair growth, abnormal sweating, weight loss, muscle wasting, abnormal fat distribution, lethargy, laminitis, polyuria/polydipsia and chronic/recurrent infections.

“Unfortunately, PPID is not a curable disease,” says Dr. John Tuttle, BIVI equine technical services veterinarian. “However, PRASCEND does offer a safe and efficacious treatment option to veterinarians and horse owners that can help reduce the clinical signs of the disease and effectively improve the quality of life of infected horses.”

While PPID is typically considered a late-stage-of-life disease in the horse, Tuttle adds that with horse owner vigilance and regular veterinary care, the disease may be detected earlier.

“Because the early symptoms of PPID may be difficult to recognize, some horses with PPID may go undiagnosed until the disease becomes more advanced,” says Tuttle. “Through regular veterinary wellness exams, oftentimes the disease can be caught earlier. By beginning treatment in the earlier stages of the disease, we are able to reduce the risk of some of the potential complications associated with PPID, such as laminitis, recurring infections, dental disease and other potential issues of uncontrolled PPID.”


Farriers often notice the early signs of PPID in horses' feet while trimming. As Cushings diseases advances, farriers are challenged to keep PPID sufferers comfortable and manage any flare-ups of chronic lamiitis. (Massachusetts farrier Allie Hayes trimming a Cushings-affected pony, photo © Hoofcare Publishing)

Not only can PRASCEND aid in the management of clinical signs of disease, the FDA approval also assures the product has been thoroughly evaluated for safety and efficacy. In addition, PRASCEND has met the standards set forth by the FDA in regard to production to preserve its identity, strength, quality, purity and consistency from batch to batch, and the product has demonstrated stability and effectiveness over time through a variety of environmental conditions.

“We are excited to offer a treatment option for horses suffering from PPID,” says Tuttle. “We encourage horse owners to continue to work with their veterinarians to find the best treatment for their horse and are confident that PRASCEND can help make a difference in the lives of horses suffering from this disease.”

PPID horses may be quite thin under all that hair. Cushings sufferers are also believed to be more highly perceptible to worms than non-sufferers. Many people clip their long-haired horses to be more aware of body condition. (photo © Hoofcare Publishing)
PRASCEND is for use in horses only. PRASCEND has not been evaluated in breeding, pregnant or lactating horses. Refer to the package insert for complete product information or contact Boehringer Ingelheim Vetmedica at 800-325-9167.

(Hoof Blog note: A web address should be available soon.)

Reference:
  1.  PRASCEND® (pergolide mesylate) [Freedom of Information Summary]. St. Joseph, MO: Boehringer Ingelheim Vetmedica, Inc.; 2011.
  2. McGowan TW, Hodgson DR, McGowan CM. The prevalence of equine Cushing’s syndrome in aged horses. In: Proceedings from the 25th American College of Veterinary Internal Medicine Forum; June 6–9, 2007; Seattle, WA. Abstract 603.
  3. Schott HC. Pars pituitary intermedia dysfunction: challenges of diagnosis and treatment. In: Proceedings from the 52nd American Association of Equine Practitioners Annual Convention; December 2–6, 2006; San Antonio, TX.
  4. Donaldson MT. Evaluation of suspected pituitary pars intermedia dysfunction in horses with laminitis. J Am Vet Med Assoc. 2004;224(7):1123–1127.

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 TO LEARN MORE


AAEP Statement on FDA Withdrawal of Pergolide for Human Use: Will It Still Be Available for Horses?

Pergolide Cleared for Equine Veterinary Use by FDA

Laminitis Research: Australian Breakthrough on Insulin Function in Equine Foot

Too Fat? Too Thin? British Court Faces Conflict Over "Abused" Horse with Cushings Disease

Cornell Laminitis Research Beneficiary of Arabian Horse Foundation Grant to Study Genetic Markers in Equine Metabolic Syndrome and Cushings Disease

Equine Pituitary Dysfunction Test Choices Analyzed by New Bolton Center's Jill Beech VMD

Three Chimneys Farm Works to Help Slew 'o Gold Keep His Cool



© Fran Jurga and Hoofcare Publishing; Fran Jurga's Hoof Blog is a between-issues news service for subscribers to Hoofcare and Lameness Journal. Please, no use without permission. You only need to ask. This blog may be read online at the blog page, checked via RSS feed, or received via a digest-type email (requires signup in box at top right of blog page). To subscribe to Hoofcare and Lameness (the journal), please visit the main site, www.hoofcare.com, where many educational products and media related to equine lameness and hoof science can be found. Questions or problems with this blog? Send email to blog@hoofcare.com.  
Follow Hoofcare + Lameness on Twitter: @HoofcareJournal
Read this blog's headlines on Facebook
 
Disclosure of Material Connection: I have not received any direct compensation for writing this post. I have no material connection to the brands, products, or services that I have mentioned, other than Hoofcare Publishing. I am disclosing this in accordance with the Federal Trade Commission’s 16 CFR, Part 255: Guides Concerning the Use of Endorsements and Testimonials in Advertising.

Friday, October 14, 2011

Bodo Hertsch: German Veterinarian, Researcher and Educator's Accidental Death Leaves an Empty Podium and an Empty Saddle

Professor Doctor Bodo-Wolfhard Hertsch, 68, a noted international researcher and educator on laminitis and navicular disease in horses, has died at Eichenhof Tremsdorf, the equestrian center he ran with his wife outside Berlin in Germany.

The cause of death being reported by German web sites is that he died of injuries after he fell from a horse.

"His death for us as humans, horses, expert riders and organizers rips a deep hole," said Peter Fröhlich, director of Landesverband Pferdesport Berlin-Brandenburg e. V. (LPBB).

As early as 1993, Dr. Hertsch was studying the microcirculation of the foot at different stages of laminitis and creating angiograms that would eventually yield to the venograms used today. His study "Microangiographic investigations in acute and chronic laminitis in the horse" examined the distal limbs of 27 horses of different breeds as well as of one donkey who were suffering from acute or chronic laminitis.

Most of us in America first met Bodo Hertsch when he spoke at the 1991 Bluegrass Laminitis Symposium, hosted by Dr. Ric Redden in Louisville, Kentucky. "Navicular Bone Microcirculation, Coffin Joint Effusion and Navicular Pathology: The Diagnosis  and Therapy of Chronic Disorders of the Distal Sesamoid Bone in Sport Horses" was the title of his first lecture. We certainly learned the word "podotrochlea" that day.

Even more prophetic, Bodo Hertsch's second lecture: "The Principle of Heel Elevation as a Possible Treatment for Acute and Chronic Laminitis in Horses". He explained to us that laminitis therapy in Germany was based on the Bolz shoe, adopted in 1939. Hertsch reviewed laminitis cases at the vet school and the rate of success of the shoe, which called for lowering the heels. He proposed instead that the heels be raised. His paper is worth reading; it was the early days of raising heels but his explanation of the Bolz shoe and the historic study of laminitis in Germany up until the outbreak of World War II is fantastic.

Dr. Hertsch has a paper on laminitis research in the current edition of Tierärztliche Praxis, the German veterinary journal that challenges the observation that laminitic horses have accelerated heel growth, or retarded toe growth; according to Dr. Hertsch, growth is uniform, but the disease causes the tubules to growth in a different direction, kink, and fold rather than growing downward.

"Growth of the hoof horn in horses with chronic laminitis" examines the correlation between rotation and/or sinking of the third phalanx (P3) and changes of horn growth on the hoof wall. Dr. Hertsch painstakingly reviewed radiographs or performed radiographs on 117 slaughtered or euthanized horses with chronic laminitis. He documented that in the chronic stage the vascularization changed according to the degree of rotation, the duration of the disease and its development.

To quote from an English version of the abstract of the paper: "A rotation angle of approximately 8° was found to predict a change in the direction of the growth of the hoof horn at the dorsal and the lateral hoof wall. In addition, a correlation between the rotation angle of P3 and the length of growth of the hoof could be highlighted. A greater angle could lead to a larger interruption of the dorsal horn growth; meanwhile the palmar/plantar horn growth appeared to be independent. A correlation between a medial/lateral rotation of the pedal bone and the length of the horn was not observed."

Dr. Hertsch's conclusion: "The direction change of the horn tubes might cause a decrease of the visible length growth of a chronic laminitic hoof. Therefore, it appears to be important to differentiate between the externally visible length of the hoof and the real growth of the horn. Apparently, the amount of horn produced is the same on the dorsal hoof wall and in the heel. In horses with moderate laminitis the horn tubes on the dorsal wall were lying in folds, with the consequence of a decreased visible length growth. Only the formation of wrinkles of the horn tubes on the dorsal hoof wall reduced the visible wall length. Formation of wrinkles of the horn tubes in the heel could not be observed.

"Interestingly, the results of this study show that the lateral rotation of P3 does not promote the formation of wrinkles of the horn tubes along the lateral or medial hoof wall. According to our results, a resection of the dorsal hoof wall might be a sensible therapeutic approach in horses with chronic laminitis showing a rotation of P3 of at least 8°."

For many years, Dr. Hertsch was with the veterinary school at the University of Hanover, but had in recent years been Director of the Department of Veterinary Medicine at the Clinic for Horses at the Free University of Berlin. After his retirement, Dr. Hertsch had a private clinic at the equestrian center, Eichenhof Tremsdorf GbR, which he ran with his wife, Ingrid.

Dr Hertsch was the organizer of many meetings in Germany and had most recently, in 2008, organized and chaired the International Symposium on Laminitis  in Berlin. In 1995, he hosted the international symposium on navicular disease. He also authored many books including The Horse's Hoof and How to Shoe It Without Nails, with Hellmuth Dallmer, and Anatomy des Pferdes, as well as many others.

"Horses are his passion: he rides them, he breeds them, he heals them," was a quote from a recent article about Dr. Hertsch.

Recently, Dr. Hertsch had been in Great Britain at Hickstead to represent Germany in a special FEI senior Nations Cup international team competition in show jumping among 38 riders who are also veterinarians. Bodo Hertsch was the champion, and he did it on Lucinda, a 15-year-old mare that he bred and raised himself.

In addition, he led the four-member German "A" Team to win.

That was just his style.

I'll miss Professor Doctor Hertsch. His research contributions are important but his vision for the future and his obvious love for and involvement with horses set him apart and above so many others.

Did any of his horses ever have laminitis? I don't know what drove him to delve so deeply into the disease, but I'm glad he did. He could have chosen any specialty but like so many of the people I know and respect, he chose the most difficult and challenging problem in the horse world and looked it in the eye.

Assistance with this article was provided in Germany by Susanna Forrest, author of the forthcoming book If Wishes Were Horses (and the blog by the same name), in Berlin, and by anatomist Christoph von Horst PhD DVM of HC Biovision in Munich. 

Photo of Professor Doctor Hertsch via Eichenhof Tremsdorf.


 TO LEARN MORE
© Fran Jurga and Hoofcare Publishing; Fran Jurga's Hoof Blog is a between-issues news service for subscribers to Hoofcare and Lameness Journal. Please, no use without permission. You only need to ask. This blog may be read online at the blog page, checked via RSS feed, or received via a digest-type email (requires signup in box at top right of blog page). To subscribe to Hoofcare and Lameness (the journal), please visit the main site, www.hoofcare.com, where many educational products and media related to equine lameness and hoof science can be found. Questions or problems with this blog? Send email to blog@hoofcare.com.  
Follow Hoofcare + Lameness on Twitter: @HoofcareJournal
Read the Hoofcare + Lameness Facebook Page
 
Disclosure of Material Connection: I have not received any direct compensation for writing this post. I have no material connection to the brands, products, or services that I have mentioned, other than Hoofcare Publishing. I am disclosing this in accordance with the Federal Trade Commission’s 16 CFR, Part 255: Guides Concerning the Use of Endorsements and Testimonials in Advertising.

Tuesday, April 05, 2011

Cornell Vet School Equine Herpes Virus Quarantine: Hospital and Barns Closed; Shoeing School, Farrier Shop Open

The following information is provided as a public service for horse owners and horsecare professionals.
The Smithy

The world-famous horseshoeing school and farrier shop at Cornell vet school is remaining open during the quarantine, according to resident farrier Steve Kraus. The shoes in the display case are part of the university's extensive collection of shoes made by Professor Henry Asmus, founder of Cornell's shoeing school in 1913; it was the first in the United States. (Flickr.com photo by Michael King)
The New York State Department of Agriculture and Markets’ animal health officials and veterinarians from the Equine Hospital at Cornell University are investigating two confirmed cases of Equine Herpesvirus 1 (EHV-1) in New York State. Both horses listed as cases of EHV-1 were inpatients of the Equine Hospital at Cornell University, and could have potentially exposed 69 other horses.

EHV-1 is a common viral infection of horses that is highly contagious and exhibits an array of symptoms, ranging from no clinical signs to neurological disorders.

Equine Park

New York State Veterinarian Dr. David Smith said, “While a common virus in horses, we are taking this situation very seriously given the large number of horses that have potentially been exposed to a highly communicable and sometimes fatal disease. To date, no other horses have showed signs, nor tested positive for the virus. However, this serves as an excellent reminder to horse owners that they should always be cautious of introducing new horses with an unknown disease status.”

“We recognize the seriousness of the Equine Herpesvirus Type 1 and other infectious diseases,” said Dr. Alfonso Torres, Associate Dean of Public Policy at the New York State College of Veterinary Medicine at Cornell University. “Thanks to our surveillance systems and access to highly sensitive testing at the New York State Veterinary Diagnostic Laboratory, we were able to rapidly identify the infectious agent and implement appropriate actions immediately to prevent the spread of the infection.”
Cornell, Large Animal Hospiltal
A quiet barn aisle at Cornell University College of Veterinary Medicine Equine Hospital, photo by Ernest Fox courtesy of Flickr.com

This incident involves two confirmed cases of EHV-1 in New York State. One was a one-day old foal that was admitted to the Equine Hospital on March 18. The foal died two days later of pneumonia, and tests revealed the presence of EHV-1 on March 25.

During the same time, a gelding was being treated at the hospital for a spinal injury. It was discharged on March 22, but became severely ill and showed neurological symptoms after arriving back at its home farm. This horse tested positive for EHV-1 on March 30. The gelding is now recovering.

In response to the two confirmed cases, both the gelding’s farm and the Equine Hospital were quarantined immediately, restricting movement and access to animals at both facilities. Horses at both facilities are being monitored closely and having their temperatures taken twice daily. So far, no animals have exhibited a fever attributable to EHV-1, which would be an early warning of the virus.

At the hospital, polymerase chain reaction (PCR) tests have also been completed for four consecutive days on all current patients. The PCR samples from all animals in the hospital are negative, indicating that no virus shedding is occurring.

20070814 Cornell Animal Hospital
The Equine Hospital is located in Cornell's extensive new complex of animal clinics on the edge of the Ithaca, New York campus. Photo by Ernest Fox, courtesy of flickr.com

As part of this on-going investigation, the Department of Agriculture and Markets is working to determine the source of the infection, as well as to identify and isolate potentially exposed horses. In doing so, Cornell has been contacting all referring veterinarians and the owners of 69 other equine patients that may have been exposed while at the Equine Hospital. The Department is also communicating with private veterinarians to provide information related to this situation, and is prepared to follow up on possible quarantines of trace-out barns of the 69 potentially exposed horses, if necessary.

At this time, neither the Department nor Cornell know of any other animals that have showed signs or tested positive for EHV-1 in association with this incident.

Nearly all horses in their lifetime will be exposed to EHV-1 at some point, and therefore it is difficult to detect as it takes on a wide range of manifestations, from a complete lack of clinical symptoms, to pneumonia, to abortion in mares, to full-blown fatal neurologic cases. The virus does not persist in the environment and is neutralized by hand soap, alcohol-based hand sanitizers, and sunlight. Transmission of the virus is mostly via direct contact with infected materials.

EHV-1 does not affect humans or dogs, cats, cattle, sheep, goats, pigs or birds; however, alpacas and llamas can be affected.

If you are the owner or caretaker of a horse that was or has been at the Equine Hospital at Cornell on or after March 18, 2011 or that may have come in contact with a potentially exposed patient, the following guidelines are recommended:
  • Isolate your animal, if possible. It is always recommended that horses returning from veterinary hospitals be isolated for three weeks when possible.
  • Check your horse’s temperature twice a day for ten days. If the temperature is 102 degrees Fahrenheit or greater, contact your veterinarian immediately.
  • If you care to test your horse, consult your veterinarian. At this time, the preferred test is PCR analysis performed on nasal swab specimens.
Since March 30, 2011, the Equine Hospital at Cornell University has been quarantined. No movement of animals between the equine barns and other Cornell facilities is permitted at this time, and the hospital is only accepting emergency cases.

Out of an abundance of caution, the quarantine at the hospital will remain in effect through April 11.

For more information on EHV-1, visit the American Association of Equine Practitioners website or check USDA APHIS brochure on the virus.


 © Fran Jurga and Hoofcare Publishing; Fran Jurga's Hoof Blog is a between-issues news service for subscribers to Hoofcare and Lameness Journal. Please, no use without permission. You only need to ask. This blog may be read online at the blog page, checked via RSS feed, or received via a digest-type email (requires signup in box at top right of blog page). To subscribe to Hoofcare and Lameness (the journal), please visit the main site, www.hoofcare.com, where many educational products and media related to equine lameness and hoof science can be found. Questions or problems with this blog? Send email to blog@hoofcare.com.
 
Follow the Hoof Blog on Twitter: @HoofcareJournal
Join the Hoofcare + Lameness Facebook Page

 
Disclosure of Material Connection: I have not received any direct compensation for writing this post. I have no material connection to the brands, products, or services that I have mentioned, other than Hoofcare Publishing. I am disclosing this in accordance with the Federal Trade Commission’s 16 CFR, Part 255: Guides Concerning the Use of Endorsements and Testimonials in Advertising.

Monday, June 02, 2008

Canker: Seldom Seen But Important to Recognize


Canker in Hoof, originally uploaded by krissid2001.

I can almost smell this photo right through the computer screen. And it doesn't smell good.

Have you ever seen a horse with hoof canker? I've only seen it a few times, but it certainly made an impact. I know that this is becoming more of a problem in horses in the USA, and people are reporting more cases all the time.

The problem is that many owners don't recognize what it is and rarely contact a veterinarian until it is so advanced that you can see it (and smell it) from across the paddock.

Another problem is that it often strikes draft horses, like this Clydesdale or Shire, so the feathers cover it.

If you see something ugly growing on the bottom of a horse's foot, either in the cleft of the frog or the sulci or in the heel bulbs, don't just assume it is a bad case of thrush that will go away when the pasture dries up or when summer comes. Canker often requires the services of a consulting vet or farrier and horses are sometimes put down because of it. Medications and soaking and diligent cleaning are all on the list of treatments.

Thanks to Krissid2001 for allowing me to blog this photo for you all.