AAEP Convention Trade Show Report: Pergolide in Treats for Cushings Horses

Wedgewood Pharmacy has introduced peppermint- and alfalfa-flavored Pergolide for Cushngs-affected horses in Gourmeds(TM) dosage form. Gourmeds are chewable, naturally-flavored tablets that are easy to administer -- and tasty as a treat. Gourmeds also is an economical medication form that costs about one-half the price of Pergolide in suspension form.

Pergolide mesylate, a drug used to treat Parkinson's disease in humans, was withdrawn voluntarily from the market in March 2007 because it was reported to carry a risk of serious heart-valve damage in humans. Equine veterinarians also prescribe the drug for horses with equine Cushing's Syndrome.

The withdrawal of the drug for human use had an unintended but serious side effect in barns, stables and pastures throughout the United States and left equine veterinarians scrambling for an alternative -- and legal -- source of this critical medicine.

Under the Animal Medicinal Drug Use Clarification Act of 1994, veterinarians are permitted to prescribe drugs intended for human use in "extra-label" uses in animals. According to the FDA's Center for Veterinary Medicine (CVM), compounding pergolide from bulk substances for animal use is permitted in response to a valid veterinary prescription to treat an affected horse. The FDA was sufficiently concerned about the market withdrawal of pergolide that it announced that it will "work with sponsors interested in seeking approval of a new animal drug application for the use of pergolide to treat Cushing's Syndrome in horses," according to Wedgewood.

Gourmeds are now available to veterinarians in the United States.

Quite a View: Fetal Feet from New Book "Hoof Problems"

Here's one of my favorite images from the new book "Hoof Problems". Do you have your copy yet? We sold out at Cornell vet school's farrier conference but have plenty more in stock now!

Click here for more information.

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Sue Dyson Will Present New Information on Imaging for Foot Lameness at AAEP Convention

Dr. Dyson specializes in sport horses at a leading diagnostic referral clinic in England.

Sue Dyson MA, VetMB, PhD, DEO, FRCVS, Head of Clinical Orthopaedics at the Animal Health Trust equine unit in Newmarket, England will present an in-depth three hour presentation on Tuesday, December 4 at the American Association of Equine Practitioners Convention at the Orange County Convention Center in Orlando, Florida.

Co-presenting with Dr. Dyson will be Kent Allen DVM of Virginia Equine Imaging.

The title of the program is “Lameness and Diagnostic Image in the Sports Horse: Recent Advances Related to the Digit” and it will be a case-by-case presentation between the two experts.

Dr. Dyson is known in the foot world for her meticulous diagnostic procedures and her documentation of imaging techniques, particularly in the foot. In recent years, she has made tremendous strides by using Scintigraphy and MRI to confirm or debunk the diagnosis of navicular disease in certain horses.

Her article in Hoofcare and Lameness #79 documented lesions in the deep digital flexor tendon that were treatable with rest and therapy. Many “navicular” horses have been re-evaluated since MRI has been in use, thanks to Dr. Dyson’s documentation. The tendon tear findings also explain why some horses appear to recover from navicular disease after being turned out to pasture and why other horses may not respond to certain types of medications.

Click here to download a PDF file of an article from the Equine Veterinary Journal by Dr. Dyson documenting 199 scans of equine feet. The file name will be EVJ07_39_340_343.pdf.

Sue obtained a Fellowship of the Royal College of Veterinary Surgeons (RCVS) for her thesis on shoulder lameness in the horse. She holds the RCVS Diploma in Equine Surgery (Orthopaedics) and is a recognized Specialist of the RCVS. She obtained a PhD from the University of Helsinki for a thesis on lameness diagnosis.

Sue Dyson is co-author of the textbook Diagnosis and Management of Lameness in the Horse and a consulting editor to Hoofcare and Lameness Journal. Her newest article is on the subtleties of identifying multiple limb lameness in horses.

Sue is a past President of the British Equine Veterinary Association. She has also ridden at top national level in both eventing and show jumping and has produced horses that have subsequently competed at the Olympics and World Championships.

Any opportunity to hear her speak is a gift. See you there.

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Les Quatre Ecoles: Snapshots from Paris

Here's a little slide show of moments at Les Quatre Ecoles d'Equestre performance in Paris last week. For the first time, four great schools of horsemanship Lisbon (Lusitanos), Jerez (Andalusians), Vienna (Lippizaners) and France's Cadre Noir performed together and demonstrated their interpretation of the high school of equestrian art.

Here's a page of links on Google Video to clips taken by spectators.

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Where's My Brumby Now: Chris Pollitt Offers Donors a Chance to Ride Along for Hoof Research...by Satellite!

I am posting a research brief from Dr. Pollitt that should be of interest to every reader of Hoofcare & Lameness Journal. I think a brumby's hoof data would make a great Christmas present! Above: Australian feral horses ("brumbies") photographed from the air by Dr Pollitt in July of 2007 while conducting preliminary research.

Australian Hoof Research Project Brief: Determining the range of the Australian wild horse (Brumby) and the relationship to foot type and conformation.

Our team has spent much of the past 12 months investigating the use of GPS technology to track the movements of horses. As a result we have developed the ideal tool to track the day-to-day movements of horses in both the domestic and wild environments.

Our GPS tracking units allow us to accurately pinpoint the location, speed and altitude of the horse at one-second intervals for up to one week or at 30-second intervals for up to six months.

Domestic horse wearing a collar with GPS tracker attached.

A GPS unit attached to a strap around the horse's neck is able to fix the position of the horse by aligning its position with at least six satellites orbiting overhead and storing the data on board. When data is retrieved, it is interfaced with Google Earth to 1) produce an aerial photograph of the horse's movements (see photo) and 2) be overlaid on a geographical mapping system which applies the data to soil and vegetation type, use of water points and topography type.

This exciting technology is being applied to horses for the first time by our research team, with the goal of establishing a complete picture of the movements of horses, both domestic and wild, and how they interact with their environment.

The effect of movement and environment on the horse’s foot is a significant focus of the research. We know from preliminary work that the typical domestic horse’s foot travels very little (approximately 7 km daily) in comparison to its wild counterpart which may travel up to 50 km or more in a single walk. We have several populations of "Brumbies" (Australian feral horses) under investigation to determine natural foot structure and function under various environmental conditions.

Tracking data (3 days) from horses grazing a large 40-acre forested paddock

We are about to embark on the most exciting part of the research: to track the wild horses. Brumbies will be darted silently from a hide with a tranquilizer, giving the team two minutes to photograph feet, place permanent markers to determine hoof wall growth rates and attach the GPS collar (see photo).

On reversal of the tranquilizer, the horse will rejoin its family band unaware of the intervention. The same horse will be recaptured using the dart gun at the end of the trial to retrieve equipment and then released back to the wild.

This work will begin in March 2008 and continue for 12 months in locations in Central and Northern Queensland and the Northern Territory and Eastern Kimberly region of Western Australia. The project will ultimately identify the relationship between a horse’s movement and the effect on foot conformation, structure and function.

Our goal is to make well-informed recommendations of the ideal conditions to keep domestic horses to improve the well-being of their feet.

You can help in this groundbreaking research. The more GPS units we can attach to wild horses, the better and more accurate the data set will be. For AUS$3000 (approx $2,600 US) you can own and name a wild horse for the 4 to 6 month tracking season. We will supply photos and location data at the time of GPS attachment and, when retrieved, we will use the GPS download from your horse to generate a report using Google Earth maps.

Ultimately, the combined data from all the horses will be compiled into freely available scientific reports.

Please help if you can.

Professor Chris Pollitt
Professor of Equine Medicine
School of Veterinary Science
The University of Queensland
St Lucia, Brisbane, Queensland AUSTRALIA
email c.pollitt@uq.edu.au
website: www.laminitisresearch.org
fax 07 3365 2351

Note: To learn more about Dr. Pollitt and his observations of brumby feet, refer to "The Natural Hoof Down Under" in Hoofcare and Lameness Issue #69. He has also been a keen observer of zebra feet in the wild.

Double-click on any photo to view it in an enlarged size but please remember that these photos are the property of Dr. Pollitt and are protected by the copyright of Hoofcare and Lameness Journal and www.hoofcare.com, to say nothing of Dr. Pollitt's six satellites circling the earth.