Research overview: Preventing laminitis by studying insulin dynamics in older horses

Laminitis research comes in many forms. Recently, the emphasis has been on understanding the cause of the disease, and developing ways to prevent horses from ever knowing laminitic pain. The emphasis is on understanding how horse management and feeding can effect hormonal balances in older horses, and what recommendations might help horses live longer and healthier lives.

Laminitis research: Even healthy older horses have increased insulin responses

New research, conducted in collaboration with the SPILLERS® horse feed company in Great Britain shows that even healthy older horses have increased insulin responses, compared to younger horses, in response to a starch-rich or starch- and sugar-rich meal.

Laminitis research: Feeding a high starch diet can influence PPID (Equine Cushings Disease) test results

Summary: New research, conducted in collaboration with the British horse feed company SPILLERS®, has shown that the equine diet, and more specifically, a starch rich food, can influence adrenocorticotropin hormone ,or ‘ACTH’, test results. This could potentially lead to an incorrect disease diagnosis in some horses when ACTH is used to test for Pituitary Pars Intermedia Dysfunction (PPID).

Key point: The threshold values for diagnosis of the disease currently vary dependent on the season, but these new findings suggest that diet should also be considered. 

Hoof Blog note: Laminitis in older horses is commonly blamed on PPID, but a definitive diagnosis by hormonal test results is required to determine if an underlying endocrine condition is the cause of laminitis. Some horses with PPID may lose weight, which might lead owners to increase feed or change to a higher-starch diet to counter weight loss. Horse owners and veterinarians should communicate about a horse's feed intake before testing; future research may reveal more specific guidelines about how feed type influences test results.